'Grey's Anatomy' Fans Crushed After Justin Chambers Exits After 15 Years

Fans are reacting after Grey's Anatomy star Justin Chambers announced his departure from the series on Friday. In a statement to Deadline, the actor, who portrays Dr. Alex Karev, explained that “hoped to diversify my acting roles and career choices.” His exit from the series will leave lead star Ellen Pompeo as the only original intern from Season 1, crushing fans.

"Justin Chambers is leaving Grey's and I am absolutely wrecked nobody talk to me," tweeted one fan.

"Honestly can't believe that Justin Chambers is leaving Greys Anatomy like wtf is happening," wrote another. "so so so sad."

"I'm not emotionally prepared to handle Justin Chambers leaving Grey's," commented one Grey’s viewer.

"2020 is cancelled. ABC can cancel Grey's Anatomy," added another. "Justin Chambers is leaving Grey's. NOT ALEX KAREV. NOT EVIL SPAWN. My heart is breaking. I'm actually crying right now."

"There's no good time to say goodbye to a show and character that’s defined so much of my life for the past 15 years," Chambers said in his statement. "For some time now, however, I have hoped to diversify my acting roles and career choices. And, as I turn 50 and am blessed with my remarkable, supportive wife and five wonderful children, now is that time."

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"As I move on from Grey's Anatomy, I want to thank the ABC family, Shonda Rimes, original cast members Ellen Pompeo, Chandra Wilson and James Pickens, and the rest of the amazing cast and crew, both past and present, and, of course, the fans for an extraordinary ride," he added.

At this time, it is unclear when Chambers' final episode will air. Grey's Anatomy returns with new episode of Season 16 on Thursday, Jan. 23 at 9 p.m. ET on ABC.